Research results

Biopsy
Biopsy of a trophectoderm (in the caul) from a blastocyst (embryo) (photo: Emma Kathrine Lorenzen)
 

On this page, you will be able to see the research results and milestone that have been achieved in the project so far as well as a list of all the scientific papers that will in time be published in international and Danish journals.

78 Effects of in vitro production on the epigenome and transcriptome of bovine embryos determined through a multi-omics data integration approach
M. Rabaglino A , J. B.-M. Secher B , P. Hyttel B and H. Kadarmideen
A Reproduction, Fertility and Development 33(2) 147-147. Jan 2021.
(doi.org/10.1071/RDv33n2Ab78)

Danish dairy farmers' acceptance of and willingness to use semen from bulls produced by means of in vitro embryo production and genomic selection.
T.B.Lund, C. Gamborg, J.Secher, P.Sandøe.
Journal of Dairy Science. Jul 2021;104(7):8023-8038.
(doi: 10.3168/jds.2020-19210)

Vitrification Yields Higher Cryo-Survival Rate Than Slow Freezing in Biopsied Bovine in vitro Produced Blastocysts.
Vahid Najafzadeh, Jan Bojsen-Møller Secher, Maria Pihl, Anna Ærenlund, Natasha Jørgensen, Karoline Kjærsgaard Jensen, Maibritt Træholt Jensen, Merle Friederike Fenner, Lotte Strøbech, Poul Hyttel.
Theriogenology. 2021 Sep 1;171:44-54.
(doi: 10.1016/j.theriogenology.2021.04.020)

Application of multi-omics data integration and machine learning approaches to identify epigenetic and transcriptomic differences between in vitro and in vivo produced bovine embryos.
Maria Belen Rabaglino, Jan Secher, Poul Hyttel and Haja Kadarmideen. PLoS One. May 2021 24;16(5):e0252096.
(doi: 10.1371/journal.pone.0252096)

Epigenomic and transcriptomic analyses reveal early activation of the HPG axis in in vitro-produced male dairy calves
María B Rabaglino, Jan Bojsen-Møller Secher, Marc-André Sirard, Poul Hyttel, Haja N Kadarmideen. 
FASEB J. Oct 2021;35(10):e21882.
(doi: 10.1096/fj.202101067R)

Oocytes, embryos and pluripotent stem cells from a biomedical perspective
Hyttel, P., Pessôa, L. V. D. F., Secher, J. B. M., Dittlau, K. S., Freude, K., Hall, V. J., ... Stroebech, L. B.
Animal Reproduction, 2019, 16(3), 508-523.
(doi: 10.21451/1984-3143-AR2019-0054)